Premier League Predicted Lineups – Gameweek 21

Welcome to our Premier League predicted lineups hub where you can find predicted lineups with data, tactical insights and injury news to back up our predictions for every Premier League game of the week, every single Gameweek of the season!

Premier League Predicted Lineups – Gameweek 21

Premier League Predicted Line-up Main Hub

Welcome to our Premier League Predicted line-ups hub. You can find every Premier League team’s predicted line-ups for the current Gameweek with data and tactical insights along with press conference and injury news to back up our predictions.

Predicted line-ups are key for Fantasy football and also in other arenas like gambling.

Why? Simply put, if you can predict a team’s starting line-up, and have the knowledge to understand what the line-up may tell us about how a team might set up tactically, or how they intend to play, then we as fans, Fantasy managers or gamblers can more accurately predict how a game might play out. Accurate predicted line-ups also help FPL managers to attack a Blank or Double Gameweek with confidence – team selection in those weeks are pivotal to FPL success. Predicted line-ups can also help us plan for when to use our chips and who to use them on. They are a great tool to maximise your FPL team, to stay up to date with injuries, tactical set ups of certain teams and to plan ahead in FPL.

 

Premier League Gameweek 21 Fixtures

Tuesday, 6 January 2026

Wednesday, 7 January 2026

Thursday, 8 January 2026

  • Arsenal vs Liverpool – 15:00 EST

(Fixtures subject to kick-off times and TV scheduling, but confirmed for this matchweek.)


Key Line-up & Team News Items Ahead of Gameweek 21

  • Guardiola confirms Dias & Gvardiol injuries “don’t look good”
    Pep Guardiola admitted that Rúben Dias and Josko Gvardiol suffered knocks in Man City’s recent draw with Chelsea and their conditions aren’t looking good for the upcoming fixtures. He emphasized the depth issue and the need to rely on academy players given City’s depleted defensive resources.

  • City’s defensive situation forces squad rotation
    With John Stones already out long-term, Guardiola will need to adjust his defensive line-ups and possibly promote youth players, highlighting the challenges City face ahead of crucial Gameweek 21 matches.

  • City may recall defensive reinforcement from loan
    Manchester City have recalled centre-back Max Alleyne from his loan spell to strengthen the squad after the injuries to Gvardiol and Dias, providing additional depth at the back.

  • Slot confirms Ekitike injury following scan
    Liverpool boss Arne Slot revealed that striker Hugo Ekitike had an MRI scan after feeling discomfort in training. Although not serious, he will miss recent games, raising doubts over his availability for GW21.

  • Hurzeler updates on Minteh & confirms Wieffer is out
    Brighton boss Fabian Hurzeler explained that Yankuba Minteh’s scan came back clear (a dead leg), but they’ll assess his ability to train and start, while Mats Wieffer remains unavailable due to a toe injury.

  • Botman “close but cautious” ahead of return
    Newcastle’s Sven Botman is reported to have trained and could be nearing a return, but Eddie Howe has urged caution before rushing him back into the squad, indicating he may not be ready immediately for Gameweek 21.

  • Guardiola stresses reliance on youth players
    In press comments, Guardiola highlighted the importance of calling up additional academy players, reflecting both tactical and injury‑coverage concerns as City juggle multiple absences.

  • Amorim sacked but hinted Fernandes return
    Manchester United manager Rubén Amorim was sacked following poor results, but in a pre-dismissal press conference, he suggested that Bruno Fernandes could return to training and potentially feature very soon, offering a boost to the squad before his departure.

  • Rice & Gabriel back with a bang

 

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